苏建俊  丁野  雷玉萍

（湖南省药品检验所  长沙410001）

关键词  银翘解毒浓缩丸  绿原酸  RP-HPLC

摘要  目的:建立银翘解毒浓缩丸的质量控制方法。方法:采用TLC法鉴别了荆芥、牛蒡子、桔梗、连翘；用RP-HPLC法测定绿原酸的含量。结果:薄层色谱斑点清晰,空白对照无干扰；绿原酸在0.0513～0.46117μg范围呈良好的线性关系，ｒ＝0.9999，平均回收率为100.52%，RSD=1.37%。结论:方法简便，结果准确，可用于该制剂的质量标准。

Quality Standard for Yinqiao Jiedu Concentrated Pills

Su Jian Jun  Lei Yu Ping  Ding Ye 

 (Hunan Provincial Institute for Drug Control, Changsha 410001, china)

Key words:  Yinqiao Jiedu Pill; chlorogenic acid; RP-HPLC

Abstract  Objective: To establish the quality control standards for Yinqiao Jiedu Concentred Pills(YJCP).  Methods: Herba Schizonepetae；Fructus Arctii；Radix Platycodonis；Fructus Forsythiae in YJCP were identified by TLC, and the content of chlorogenic acid was determined by RP-HPLC. Result: The TLC spots were quite clear and the blank test showed no interference. The chlorogenic acid showed a good linear relationship at a range of 0.0513～0.46117μg ( r=0.9999) and the average recovery was 100.52%, RSD = 1.37%.  Conclusion: The method is simple and feasible for the quality control of the preparation.