孙慧伶 乐岭 向光大 徐琳 赵林双 侯洁 (广州军区武汉总医院 武汉 430070)
摘 要 目的：观察超短效人胰岛素类似物赖脯胰岛素（优泌乐，Lispro）与短效胰岛素诺和灵R（Novolin R）在强化治疗中的疗效差异。方法： 60名2型糖尿病患者随机分为两组，胰岛素泵治疗1周，观察两组治疗前后不同时间点血糖值变化、达标时间、胰岛素用量及有无低血糖发生。结果： Lispro组较Novolink R组血糖达标时间短、胰岛素用量少、两组均未发生低血糖。结论：在胰岛素泵强化治疗中Lispro更具优势。
关键词 赖脯胰岛素; 诺和灵R; 胰岛素泵
中图分类号：R977.1+5
文献标识码：A
文章编号：1008-049X(2007)05-0487-02
Study of Insulin Lispro and Novolin R in Intensification Therapy on Diabetes Mellitus
Sun Huiling, Yue ling,Xiang Guangda, Xu lin,Zhao Linshuang,Hou jie ( Wuhan General Hospital of Guangzhou Command, Wuhan 430070,China)
ABSTRACT Objective: To observe the difference of therapeutic effect between supershorteffect insulin analog lispro and shorteffect insulin novolin R on diabetes patients. Method: Sixty type 2 diabetes mellitus patients were divided into two groups and received insulin pump therapy for 2 weeks. The plasma glucose at different time after therapy, period of reaching target, total insulin dosage and whether hypoglycaemia happened were observed. Result: Period of reaching target of Lispro group was shorter than novolin R group, and total insulin dosage was less than novolin R group. There were no hypoglycaemia happened in neither groups.Conclusion: Lispro had an advantage comparing with novolin R in insulin pump intensification therapy.
KEY WORDS Insulin lispro; Novolin R; Insulin pump
参 考 文 献
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