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抗流感病毒化学药物的临床应用-07.6

阅读: 时间: 2007-6-15 10:25:00

李瑛  樊迎春  张伟  李旻  (湖北省丽益医药科技有限公司,湖北省抗病毒药物重点实验室  武汉 430061)

关键词  流感; 化学药物; 临床

中图分类号:R978.7

文献标识码:A

文章编号:1008-049X(2007)06-0587-03

    流行性感冒(简称流感),是由流感病毒引起的一种呼吸道传染病。流感病毒属正粘病毒科,系单链RNA病毒,分为甲(A)、乙(B)、丙(C)三型,根据表面糖蛋白抗原结构和基因编码的不同,已经发现甲型流感病毒存在15种血凝素(HA)亚型和9种神经氨酸酶(NA)亚型,常引起流感大暴发。乙型流感病毒HA和NA型均只有一种,因此它没有亚型,不会造成大流行。丙型流感病毒通常只引起零星的感染,多数没有症状,不构成公共卫生关心的问题。……

参  考  文  献

1  殷璐,蒋建东.抗流感病毒研究进展[J].中国新药杂志,2004,13(8):685-687
2  Galbraith AW, Schild AW, Schild GC, et al. The therapeutic effect of amantadine in influenza occurring during the winter of 1971-1972 assessed by doubleblind study[J]. JR Coll Gen Pract, 1973,23:3437
3  世界卫生组织.〖HTK〗世界卫生组织流感大流行期间疫苗和抗病毒药品使用指南〖HTSS〗[M].第2004年版
4  运嫦. 世纪病毒H5N1——两种药物能治此病毒[N].星岛日报,1997-12-8.A2版
5  Frederick G, Hayden MD. Antiviral Resistance in Influenza VirusesImplications for Management and Pandemic Response[J]. N   Eng  Med, 2006,354(8):785-788
6  Hayden FG, Atmar RL, Schilling M, et al. Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza[J]. N Engl J Med, 1999,341:1336-1343
7  Le Guyeder F. Evaluation of a degenerate primer for the PCR detection of human euliciviruses[J]. Arch Viml,1996,4:2225-2235
8  Nicholson KG, Aoki FY, Osterhaus ADME,et al. Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial[J]. Lancet,2000,355:1845-1850
9  Aoki F. Maximising benefits of influenza treatment with oral oseltamivirresults of the IMPACT study[R]. 40th ICAAC, Toronto, Canada, September 17-20, 2000
10  The MIST (Management of Influenza in the Southern Hemisphere Trialists) Study Group. Randomised trial of efficacy and safety of inhalcd zanamivir in treatment of influenza A and B virus infections[J]. Lancet,1998,352:1877-1881
11  Murphy KR, Eivindson A, Pauksens K, et al. Efficacy and safety of inhaled zanamivir for the treatment of influenza in patients with asthma or chronic obstructive pulmonary disease[J]. Clin Drug Invest, 2000,20: 337-349
12  Elena AG. Comparision of Efficacies of RWJ270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza Viruses[J]. Antimicrobial Agents And Chemotherapy, 2001,45(10),2723-2732
13  Mitamura K, Sugaya N, Nirasawa M,et al.Kansenshogaku zasshi 2002  76(11):946-952
14  Reisinger K, Hayden FG, Whitley R, et al. Oral oseltamivir is effective and safe in the treatment of children with acute influenza[R].10th European Congress of Clinical Microbiology and Infectious Diseases, Stockholm, Sweden,May 28-31, 2000
15  江西省食品药品监督管理局. 江西省食品药品监督管理局药物警戒快讯,2005,14
16  卢洪洲,张永信.人禽流感的抗病毒治疗[J].世界临床药物,2004.25(3):134-137
17  Douglas RGJ. Prophylaxis and treatment of influenza[J]. N Eng J Med,1990,322:443
18  Lalezari J.  The efficacy and Safety of inhaled zanamivir in the treatment of influenca A   and  B in high risk individuals results of phase 2 and 3 clinical studies[R].In Abstracts of the 39th interscience conference on Antimicrobial Agents and Chemotherapy.Washington,DC: Am Soc Microbiol,1999,420
19  比阿尼,徐宁,陈智.流行性感冒治疗中的神经氨酸酶抑制剂[J].国外医学流行病学传染病学分册,2004,31(2):102-107

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