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单克隆抗体治疗肿瘤的研究概况-07.6

阅读: 时间: 2007-6-15 15:14:00

杜光  刘东  (华中科技大学同济医学院附属同济医院药学部  武汉 430030)

关键词  单克隆抗体; 肿瘤; 治疗

中图分类号:R730.5

文献标识码:A

文章编号:1008-049X(2007)06-0547-03

    化疗是肿瘤治疗的重要手段,目前现有的化疗药物普遍选择性不高,在杀伤肿瘤细胞的同时也可能损害体内某些类型的正常细胞,常出现较明显的毒副反应,因此肿瘤靶向治疗已成为提高治疗效果的一条重要途径。而肿瘤相关抗原及其相应的单克隆抗体(monoclone antibody, mAb)的出现,使得制备一种具有选择性抗肿瘤作用的药物的研究有了很大的发展。……

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