张伟标 廖宇忠 陈志龙 (兴宁市人民医院 广东兴宁 514500)
摘 要 目的：了解2003～2005年我院常见病原菌分布与耐药状况。方法：采用SENSITITRE全自动微生物鉴定系统对分离的菌种和药敏结果进行分析鉴定。结果：大肠埃希杆菌、表皮葡萄球菌、铜绿假单胞菌、肺炎克雷伯菌、金黄色葡萄球菌分离率排列在前五名。氨苄西林、四环素对前五位细菌耐药率均高于75%。头孢他啶、头孢哌酮对大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌的耐药率低于26.8%。SMZ对表皮葡萄球菌、金黄色葡萄球菌的耐药率低于20%。结论：常见病原菌的耐药性日益严重。细菌药敏试验及针对不同细菌选用敏感抗菌药物是合理应用抗菌药的前题。
关键词 耐药率；细菌；分离率
中图分类号：R978.1
文献标识码：A
文章编号：1008-049X(2007)07-0682-03
Bacteria Isolation and Antibiotic Resistant Monitoring from Our Hospital
Zhuang weibiao,Liao Yuzhong, Chen zhilong (Dept.of Pharmacy,Guangdong Xingxin City People's Hospital, Xingxin. 514500，China)
ABSTRACT Objective: To investigate the distribution and drug resistance of common bacterial isolated from our hospital during 2003-2005.
Method: The isolated strains and drug sensitivity test by SENSITITER automaticity microbe assay system were analyzed and identified.Result:The most prevalent isolated strains were bacillus coli, staphylococcus epidermidis, pseudomonas aeruginosa (PA), klebsiella pneumoniae and staphylococcus aureus . The resistance rate of bacteria which rank in the first 5 place to ampicillin and tetracycline were above 75%. The resistance rate of bacillus coli, PA and klebsiella pneumoniae to ceftazidime and cefoperazone were below 26.8%. The resistance rate of staphylococcus epidermidis and staphylococcus aureus to SMZ was below 20%.
Conclusion: The drug resistance of common bacteria is serious day by day.The drug sensitivity test of bacteria and the selection of sensitive antibacterial drugs are the premise of rational use of anti-bacterial drugs.
KEY WORDS Dyug resistance; Bacteria; Isolation rate
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