王晓玲1 林琛2 郭奇慧1 (1.洛阳市药品检验所 河南洛阳 471003; 2.河南大学药学院学生)
摘 要 目的：研究不同蒸干条件对藿香正气水中厚朴酚与和厚朴酚的含量测定的影响。方法：以厚朴酚与和厚朴酚的含量为指标，采用不同蒸干温度及不同蒸干后放置时间，用HPLC法测定厚朴酚与和厚朴酚的含量。结果:各温度下，随时间延长含量测定结果呈下降趋势。结论：对藿香正气水中厚朴酚与和厚朴酚的含量测定时，温度是重要影响因素，操作时应避免高温及在高温下长期放置。
关键词 藿香正气水；厚朴酚；和厚朴酚
中图分类号：R927.2
文献标识码：A
文章编号：1008-049X(2007)10-0991-03
Influences of Assay of Magnolol and Honokiol in Huoxiang Zhengqi Solution under Different Conditions of Evaporation to Dryness
Wang Xiaoling1, Lin Chen2, Guo Qihui1 (1.Luoyang Institute for Drug control,Henan,Luoyang 471003,China;2.Student of School of Pharmacy,Henan University)
ABSTRACT Objective:To study the influences of assay of magnolol and honokiol in Huoxiang Zhengqi solution under different conditions of evaporation to dryness.Method:The different temperatures of evaporation were used to dryness and allow to stand times for different times after evaporation,the contents of magnolol and honokiol were used as makers,the contents were determined by HPLC.Result:At different temperatures,the result of assayings was a downtrend with the time extended.Conclusion:The temperature is an important factor while assaying the magnolol and honokiol in Huoxiang Zhengqi solution and it should be avoided to keep them at high temperatures for a long time while operating.
KEY WORDS Huoxiang Zhengqi solution;Magnolol;Honokiol
参 考 文 献
1 王风玲,江云丽.藿香正气水引起醉酒貌样过敏反映1例［J］.药物流行病学杂志,2002,11(5)：267
2 苏子仁，董婷霞，卢振强,等.高温致厚朴SFE-CO2萃取物中厚朴酚、和厚朴酚降解［J］.药学学报，2002,37(11)：870-875
3 中国药典［S］.2005年版一部.661
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