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长春碱类药物与中药复方联合运用治疗肺癌的进展
Application Progress in Vinblastines Combined with Traditional Chinese Medicine in the Treatment of Lung Cancer
投稿时间:2017-05-15  修订日期:2017-05-27
DOI:
中文关键词:  长春碱类  化疗  中药复方  肺癌  增效减毒
英文关键词:Vinblastines  Chemotherapy  Chinese herbal compound  Lung cancer  Synergistic and attenuated effects
基金项目:
作者单位
岳晨 王贤正 赵黎 谢鸣 北京中医药大学方剂学系 北京 100029 
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中文摘要:
      摘 要长春碱类药物作为第三代化疗药物被广泛应用于多种癌症的治疗,其中长春瑞滨(NVB)是治疗非小细胞肺癌的一线化疗药物,但因不良反应限制了其在临床的运用。有较多的临床研究显示,中医药与NVB及其化疗方案合用有提高抑瘤效果,改善患者生活质量,增强患者免疫力,减轻化疗引起的胃肠道反应、骨髓抑制等作用。本文就近十多年来中药联合长春碱类化疗治疗肺癌的进展进行评述。
英文摘要:
      ABSTRACTVinblastines as third generation chemotherapy drugs are widely used in the treatment of a variety of cancers. Among them, vinorelbine (NVB) is a first line chemotherapy drug for non small cell lung cancer, while its side effects often limit its clinical use. There are more and more clinical studies show that Chinese medicine and NVB in the chemotherapy program has a synergistic anti tumor effect, which can improve quality of life and immunity of patients, and reduce such side reactions as gastrointestinal reactions, bone marrow suppression and so on. In this paper, the application progress in traditional Chinese medicine combined with vinblastine in the treatment of lung cancer in recent ten years was reviewed.
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